Studies

Immunovet: can be used effectively to maintain the health of liver cells

Immunovet: can be used effectively to maintain the health of liver cells

In a recent study, Immunovet proved to be an effective liver protector in case of damage caused by bacterial toxins when tested on liver cells isolated from rats.

In a recent study, Immunovet proved to be an effective liver protector in case of damage caused by bacterial toxins when tested on liver cells isolated from rats.

The liver can be considered the central organ of metabolism and detoxification in both human and animal bodies. Substances taken in during nutrition, including potentially toxic compounds, after absorption from the intestine, go directly to the liver, where they undergo various chemical transformations before entering the central blood circulation, which then transports them to all the cells of the body. In the case of toxins, the purpose of the reactions taking place in the liver is to dispose of the dangerous substances before they reach other vital organs. At the same time, it follows that the liver is the organ most exposed to the effects of toxic compounds, which plays an essential protective role against ingested toxic substances. Oxidative stress often develops during liver damage, which can be mitigated by administering antioxidant liver protectors.

In a recent study at the University of Veterinary Medicine, the effect of Immunovet was investigated on liver cells isolated from rats. The cells were infected with Salmonella enterica ser. He was treated with toxins from the Typhimurium bacterium, which is a bacterium that very often causes intestinal infections in our pets. In addition to the toxin, the cells received Immunovet, as well as the active ingredient of two drugs used as liver protectors for comparison. They investigated whether Immunovet is able to reduce the oxidative stress caused by the toxin in liver cells, given that in previous studies it was already proven to have an antioxidant effect on other cell types.

During the experiments, they found that Immunovet was able to significantly reduce the oxidative stress caused by the bacterial toxin on liver cells: as a result, the production of free radicals in the cells was lower, as well as the amount of molecules indicating damage to the cell membrane. The effect of Immunovet was similar to the active ingredients of the two commercially available drugs. In summary, Immunovet can be used effectively to maintain the health of liver cells.

Source:
Gábor Mátis, Máté Mackei, Kata Oláhné Orbán, Zsuzsanna Neogrády, Ákos Jerzsele (2019): The effect of fermented wheat germ extract (Immunovet®) on the redox homeostasis of the liver. In vitro studies on rat primary liver cell cultures. Research report. ÁTE Department of Biochemistry and ÁTE Department of Pharmacology and Toxicology.