Studies
Immunovet: significant cell protection effect against the toxins of feed molds
In a recent study at the University of Veterinary Medicine, the protective effect of Immunovet against mold toxins was investigated.
In a recent study at the University of Veterinary Medicine, the protective effect of Immunovet against mold toxins was investigated.
Mycotoxins are toxic compounds produced by various molds, which can occur in the seeds of cereals if the plant has been infected by a fungus in the field. This is most common in warm, humid periods, when the infection rate of plants can be as high as 50-60%. Toxins in food and feed can damage the health of our pets in many ways: they cause apoptosis, i.e. cell death, in the cells of the immune system, they trigger oxidative stress, and they have a negative effect on the integrity of the intestinal epithelium, the latter of which is absolutely necessary in order to perform the proper absorptive and protective function of the intestine.
In a recent study conducted at the University of Veterinary Medicine, the protective effect of Immunovet against various mycotoxins was investigated. Intestinal epithelial cells were treated with DON and T-2 toxins, as well as their combination, which are among the mycotoxins most frequently occurring as contaminants of feed. The effect of Immunovet on cells was analyzed independently and in combination with toxins. In order to learn about the damage and the possible protective effect, the viability of the cells, the integrity of the cell layer, and the amount of molecules indicating oxidative stress were measured.
Immunovet alone increased cell viability and cell layer integrity. When administered in combination with mycotoxins, it showed a protective effect against the oxidative stress and loss of integrity caused by the toxins. Based on the results, Immunovet can contribute to maintaining the healthy cellular function of the animal body in case of contamination of feed with mycotoxins.